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Grade 9 / Middle 3 (age 14-15)

grade 9 Cell Division

Cell Division (Mitosis)

Double the side of a cube and its surface area grows four times while its volume grows eight times. Cells are the same: if one grows too big, its surface cannot keep up with its volume for taking in what it needs and getting rid of wastes, so at a certain size it divides in two. In mitosis the cell first copies its DNA during interphase, then passes through prophase, metaphase, anaphase and telophase to make two daughter cells with the same number of chromosomes as the parent. Stepping through the diagram, X-shaped chromosomes line up across the middle of the cell, split into two strands that are pulled to opposite ends, and the cell divides into two. The extra cells this produces are what let the body grow and wounds heal.

Why Do Cells Divide?

🔬 Bigger Is Worse for a Cell
①As a cell grows, its volume increases with the cube of its length but its surface only with the square, so volume grows much faster
②When surface area is small compared with volume, exchanging materials becomes hard
③So once a cell reaches a certain size, it divides instead of growing larger
④A many-celled organism grows because the number of its cells increases

Stages of Mitosis

Interphase
📖 What Happens at Each Stage
①Interphase: DNA is copied; this takes up most of the cell cycle
②Prophase: the loose, thread-like chromatin coils into X-shaped chromosomes, the nuclear membrane breaks down and spindle fibers form
③Metaphase: the chromosomes line up across the middle of the cell (the equatorial plate)
④Anaphase: spindle fibers pull the two chromatids of each chromosome to opposite ends
⑤Telophase: nuclear membranes re-form and the cytoplasm divides, giving two daughter cells

Summary

Result of mitosis
Parent cell (2n chromosomes) → 2 daughter cells (2n each)
The DNA is copied and then shared equally, so each daughter cell has the same chromosomes and genetic information as the parent
Cell cycle
Interphase (G₁ → S → G₂) → mitotic phase (M)
Interphase takes about 90 % of the cell cycle, and DNA is copied in the S phase
🎯 Common Test Points
①Order of mitosis: interphase → prophase → metaphase → anaphase → telophase
②Metaphase: chromosomes are thickest and shortest, so they are easiest to observe
③Anaphase: the chromatids separate, so the number of chromosomes in the cell briefly doubles
④Daughter cells have the same number of chromosomes as the parent
⑤Mitosis is how organisms grow and repair themselves

Examples and Unit Review

Example 1
After interphase, in what order does mitosis proceed, and at which stage do the chromosomes line up across the middle of the cell?
1
After the DNA is copied in interphase, division runs prophase → metaphase → anaphase → telophase.
2
The chromosomes line up across the middle of the cell (the equatorial plate) in metaphase, when they are easiest to see.
▸ Interphase → prophase → metaphase → anaphase → telophase; they line up in metaphase
Under a microscope, an onion root tip shows cells at many stages, and most of them are in interphase.
Example 2
How do mitosis and meiosis differ in the number of divisions and the chromosome number of the daughter cells? (The parent cell has 2n chromosomes.)
1
Mitosis divides once and makes 2 daughter cells with the same chromosome number as the parent (2n).
2
Meiosis divides twice in a row and makes 4 sex cells with half the chromosome number (n).
▸ Mitosis: 1 division, 2 daughter cells, 2n. Meiosis: 2 divisions, 4 daughter cells, n
Because meiosis halves the chromosome number, offspring still have 2n chromosomes after a sperm and an egg join.
Unit Test
Which statement about cell division is correct?
①In mitosis the chromosome number is halved
②Meiosis divides only once
③In metaphase of mitosis the chromosomes line up at the equator
④Nothing happens during interphase
⑤In anaphase the chromosomes gather at the equator
▸ ③ In metaphase of mitosis the chromosomes line up at the equator
1
In mitosis the chromosome number stays the same (① wrong, meiosis halves it), and meiosis divides twice in a row (② wrong).
2
DNA is copied during interphase (④ wrong), and in anaphase the sister chromatids move to the poles while alignment at the equator is metaphase (⑤ wrong); in metaphase of mitosis the chromosomes line up at the equator (③ correct).

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